The PDIM paradox of Mycobacterium tuberculosis: new solutions to a persistent problem
C. V. Mulholland, T. J. Wiggins, J. Cui, C. Vilcheze, S. Rajagopalan, M. W. Shultis, E. Z. Reyes-Fernandez, W. R. Jacobs, M. Berney
The paper identifies a metabolic deficiency causing PDIM loss in Mycobacterium tuberculosis and shows how nutrient supplementation can restore PDIM production and virulence.
bioRxiv · Oct 16, 2023Microbiology