An anaphase switch in astral microtubule dynamics specifically requires the APC/C-Cdc20-dependent degradation of the mitotic cyclin Clb4
F. Zucca, J. Li, C. Visintin, S. P. Gygi, R. Visintin
The paper shows that APC/C-Cdc20-dependent degradation of Clb4 is required for the anaphase switch in astral microtubule dynamics, crucial for spindle orientation.
bioRxiv · Apr 21, 2022Cell Biology