Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1
G. Kozlov, J. Jiang, T. Rutherford, A. Noronha, C. Wilds, K. Gehring
This study investigates LARP1's preference for singly guanylated poly(A) RNA sequences and shows cyclic di-nucleotides bind with sub-micromolar affinity.
bioRxiv · May 8, 2024Biochemistry