Author

T. Rutherford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. B. Alvero· 2 shared A. Fox· 2 shared G. Mor· 2 shared H. Chehade· 2 shared R. Gogoi· 2 shared A. Noronha· 1 shared B. Almassian· 1 shared B. Madina· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

A. B. Alvero

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3 papers

Recent·Most cited

Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1

G. Kozlov, J. Jiang, T. Rutherford, A. Noronha, C. Wilds, K. Gehring

This study investigates LARP1's preference for singly guanylated poly(A) RNA sequences and shows cyclic di-nucleotides bind with sub-micromolar affinity.

bioRxiv · May 8, 2024Biochemistry

Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

Y. Zhang, R. Tedja, M. Millman, T. Wong, A. Fox, H. Chehade, M. Gershater, N. Adzibolosu, R. Gogoi, M. Anderson, T. Rutherford, Z. Zhang, M. Chopp, G. Mor, A. B. Alvero

This study identifies adipose-derived exosomal miR-421 as a regulator of CBX7 expression, promoting ovarian cancer metastasis by inducing epigenetic changes.

bioRxiv · Nov 7, 2023Cancer Biology

Immune modulation of innate and adaptive responses restores immune surveillance and establishes anti-tumor immunological memory

A. B. Alvero, A. Fox, B. Madina, M. Krady, R. Gogoi, H. Chehade, V. Nakaar, B. Almassian, T. O. Yarovinsky, T. Rutherford, G. Mor

This paper develops CARG-2020, a virus-like-vesicle that modulates immune responses to enhance anti-tumor immunity and establish immunological memory in ovarian cancer.

bioRxiv · Sep 27, 2023Immunology