C. Witzany

The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures

This study shows that random antimicrobial peptide mixtures reduce resistance evolution in Pseudomonas aeruginosa compared to single peptides, preventing cross-resistance and maintaining drug sensitivity.

Assessing the importance of resistance, persistence and hyper-mutation for antibiotic treatment success with stochastic modelling

This study uses stochastic modelling to show that antibiotic treatment failure can result from resistance, persistence, or hyper-mutation, with distinct dependencies on antibiotic concentration and timing.