Z. Hayouka

This study evaluates a 16-residue peptide from Medicago truncatula defensin for its ability to penetrate mammalian cells and deliver cargo, showing efficient uptake and minimal cytotoxicity.

This paper develops a method to reactivate the complement system against complement-resistant bacteria by conjugating a peptide binder to a complement protein, achieving 90% eradication of E. coli.

The paper designs a peptide-based QS inhibitor that reduces Bc virulence by blocking immune system eradication in mouse models.

The paper shows that a C-terminal peptide from CSNAP can displace CSNAP from the CSN complex, reducing CSN activity and CRL function, suggesting a new therapeutic approach.

This study shows that combination antimicrobial peptide treatments can delay and reduce the evolution of resistance in S. aureus compared to single AMPs.