Development of Small Molecule Inhibitors Targeting PBX1 Transcription Signaling as a Novel Cancer Therapeutic Strategy
T.-L. Wang, I.-M. Shih, Y.-A. Shen, J. Jung, G. D. Shimberg, F.-C. Hsu, Y. S. Rahmanto, S. L. Gaillard, J. Hong, J. Bosch, C.-M. Chuang
This study develops small molecule inhibitors targeting PBX1 transcription signaling, showing they suppress cancer cell growth and re-sensitize resistant tumors.
bioRxiv · Apr 19, 2021Pathology