Author

C.-Y. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. T. Lehrer· 3 shared L. Pessaint· 3 shared M. M. Lieberman· 3 shared T. A. S. Wong· 3 shared A. To· 2 shared H. Andersen· 2 shared O. Donini· 2 shared A. Cook· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersImmunology

A. T. Lehrer

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3 papers

Recent·Most cited

Protein Vaccine Induces a Durable, More Broadly Neutralizing Antibody Response in Macaques than Natural Infection with SARS-CoV-2 P.1

A. To, T. A. S. Wong, M. M. Lieberman, K. S. Thompson, L. Pessaint, J. Greenhouse, N. Daham, A. Cook, B. Narvaez, Z. Flinchbaugh, A. Van Ry, J. Yalley-Ogunro, H. Andersen, C.-Y. Lai, O. Donini, A. T. Lehrer

A recombinant subunit vaccine with CoVaccine HT adjuvant provides durable, broad neutralizing antibodies against SARS-CoV-2 VOCs in macaques, outperforming natural infection in protection and viral load reduction.

bioRxiv · Sep 24, 2021Immunology

Recombinant protein subunit SARS-CoV-2 vaccines formulated with CoVaccine HT adjuvant induce broad, Th1 biased, humoral and cellular immune responses in mice

C.-Y. Lai, A. To, T. A. S. Wong, M. M. Lieberman, D. E. Clements, J. T. Senda, A. H. Ball, L. Pessaint, H. Andersen, O. Donini, A. T. Lehrer

bioRxiv · Mar 2, 2021Immunology

CoVaccine HT™ adjuvant potentiates robust immune responses to recombinant SARS-CoV-2 Spike S1 immunisation

B. K. Haun, C.-Y. Lai, C. A. Williams, T. A. S. Wong, M. M. Lieberman, L. Pessaint, H. A. Elyard, A. T. Lehrer

This study evaluates the adjuvant CoVaccine HT in SARS-CoV-2 Spike S1 vaccines, showing it enhances IgG titres, affinity maturation, class switching, and cell-mediated immunity compared to Alhydrogel.

bioRxiv · Jul 24, 2020Immunology