A new double reporter strategy reveals a subset of non-migratory hematopoietic stem cells localized in a dynamic bone marrow niche.
Marine A. Secchi, Qi Liu, Sara González Antón, Cera Mai, Aisha Souleiman Jibril, Jiarui Xu, Dónal O’Carroll, Nicola K. Wilson, Kamil R. Kranc, Berthold Göttgens, Cristina Lo Celso, Tiago Cunha Luis
This paper introduces a double reporter strategy to identify a non-migratory subset of hematopoietic stem cells in the bone marrow niche and shows their dynamic interactions during stress and aging.
bioRxiv · Jul 20, 2025 · PreprintCell Biology