Using the simple telegraph model to decipher transcriptional burst regulation across genome-wide data
Liang Chen, Yuwen Wu, Chengkai Yang, Sijia Fang, Yu Liao, Yueheng Wu, Hongkun Zhang, Guozhi Jiang, Jianshe Yu, Feng Jiao
The paper uses a simplified telegraph model to analyze transcriptional burst regulation in scRNA-seq and smFISH data, revealing key regulatory patterns in mouse and human tissues.
iScience · Aug 21, 2026Peer-reviewedMolecular Biology