Minimal biophysical rules are sufficient for the emergence of computational intelligence at the neuronal scale
Guanyu Wang, Liang Qi, K E X I N Li, Chenyu Tang, Xuhang Chen, Luigi G. Occhipinti, Arokia Nathan, Hongtao Wang, Yu Pan, Peter S. Smielewski, Ying Wang, Yingyan Mao, Xiaoyu Guo, Shuo Gao
The paper shows that minimal biophysical constraints can generate a connectome matching a mouse V1 microcircuit and enable a neural network to perform auditory classification.
bioRxiv · Mar 25, 2026 · PreprintNeuroscience