DEPP1 connects nutrient and oxygen availability to maintenance of muscle mass
Shariq Qayyum, Christopher Lavallee, Madhu Singh, Gregory A. Wyant
This study identifies DEPP1 as a new atrogene that mediates muscle loss under nutrient or oxygen limitation by linking FoxO and HIF pathways.
bioRxiv · Sep 27, 2026 · PreprintPhysiology