Author
Washington University in St. Louis
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
Jiang Tan, Monica F. Sentmanat, Yukiv Wu, Cody Peng, Catrina C. Fronick, Christopher Markovic, Xiaoxia Cui, R J Fulton, Richard Head, Ting Wang, Yidan Sun
The paper develops Nanopore-HiChIP to map enhancer hubs and shows they buffer allelic regulatory variation through kinetic compensation, preserving balanced transcriptional output.
bioRxiv · Sep 21, 2026 · PreprintGenomics
Julian Lucas, Prajna Hebbar, Wen‐Wei Liao, Juan F Macias-Velasco, Adam M. Novak, Mobin Asri, Jennifer Balacco, Andrew P. Blair, Jana Ebler, Joshua M.V. Gardner, Margarita Geleta, Cristian Groza, Andrea Guarracino, Peter Heringer, Glenn Hickey, , Jane E. Loveland
460 haplotypes from 230 genomes, selected to maximize common-variant coverage, capture 99.43% of All of Us common small variants and halve structurally unreliable regions and base errors versus HPRC1.
bioRxiv · Jul 22, 2026 · PreprintGenomics✦ In-depth digest
Monika Čechová, Tamara Potapova, Andreas Rechtsteiner, Glenn Hickey, Rebecca Serra Mari, Mira Mastoras, Julian M. Menendez, Nikol Polakova, Prajna Hebbar, Fedor Ryabov, Hailey Loucks, A.C. Gittenberger-de Groot, Tomas Pavlik, Mobin Asri, Shihua Dong, , Karen H. Miga
The paper presents T2T reference genomes from a multi-generational pedigree to study genetic and epigenetic inheritance across the complete genome.
bioRxiv · Dec 16, 2025 · PreprintGenomics
Yingxi Wang, Eleanor I. Sams, Rachel Slaugh, Sandra Crocker, Emily Cordova Hurtado, Sophia Tracy, Ying‐Chen Claire Hou, Christopher Markovic, Kostandin Valle, Victoria Tate, Khadija Belhassan, Elizabeth L. Appelbaum, Titilope M. Akinwe, Rodrigo Tzovenos Starosta, Yang Cao, , Tychele N. Turner
This study uses whole-genome sequencing to analyze 9p deletion and duplication syndromes, identifying key genes and structural variants, and introduces a machine learning model for syndrome prediction.
Genome Medicine · Oct 24, 2025Peer-reviewedGenetic & Genomic Medicine
Mohamed Mahgoub, Haley Abel, Nidhi Davarapalli, Heidi Struthers, Emilee N. Kotnik, Brittany Johnson, Christopher Markovic, Catrina C. Fronick, Robert S. Fulton, Michael P. Meers, David H. Spencer
The paper identifies intermediate methylation regions in normal cells as epimutation hotspots in cancer, showing they are prone to clonal epimutations in leukemia and other cancers.
bioRxiv · Sep 18, 2025 · PreprintGenomics
Arang Rhie, Sergey Nurk, Monika Čechová, Savannah J. Hoyt, Dylan J. Taylor, Nicolas Altemose, Paul W. Hook, Sergey Koren, Mikko Rautiainen, Ivan A. Alexandrov, Jamie Allen, Mobin Asri, Andrey V. Bzikadze, Nae-Chyun Chen, Chen-Shan Chin, , Adam M. Phillippy
The paper presents the complete sequence of a human Y chromosome, correcting errors in the GRCh38 reference and adding over 30 million base pairs.
Nature · Aug 23, 2023Peer-reviewedGenomics
Karen H. Miga, Sergey Koren, Arang Rhie, Mitchell Robert Vollger, Ariel Gershman, Andrey V. Bzikadze, Shelise Y. Brooks, Edmund Howe, David Porubskỳ, Glennis A. Logsdon, Valérie Schneider, Tamara Potapova, Jonathan M. D. Wood, William Chow, Joel C. Armstrong, , Adam M. Phillippy
The paper presents a gapless, telomere-to-telomere assembly of the human X chromosome using ultra-long-read nanopore sequencing and complementary technologies.
Nature · Jul 14, 2020Peer-reviewedBioinformatics