Reconstructing signaling histories of single cells via perturbation screens and transfer learning
Nicholas T. Hutchins, Miram Meziane, Claire Lu, Maisam M. Mitalipova, David S. Fischer, Pulin Li
The paper develops a framework combining perturbation screens and transfer learning to reconstruct signaling histories in cells and optimize differentiation protocols.
Nature Methods · Sep 8, 2026Peer-reviewedDevelopmental Biology