Temperature and Excipient Mediated Modulation of Monoclonal Antibody Interactions Revealed by kD, Rheology, and Raman Spectroscopy
Olivia Noelle Eskens, Sabitoj Singh Virk, Akashdeep Singh Virk, Deepika Venkataramani, Maureen Crames, Maria Calderon Vaca, Matthew Matusewicz, Connor Smith, Joshin George, Collin Taylor, Michael S. Marlow, Samiul Amin
This study investigates how temperature and excipients modulate monoclonal antibody interactions using kD, rheology, and Raman spectroscopy, revealing strategies to improve formulation stability.
mAbs · Jun 25, 2025Peer-reviewedBiophysics