Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy
Aksel D. Laudon, Zhaoze Wang, Anqi Zou, Richa N. K. Sharma, Jiayi Ji, Winston Tan, Connor Kim, Yingzhe Qian, Qin Ye, Hui A. Chen, J. M. Henderson, Chao Zhang, Vijaya B. Kolachalama, Weining Lu
This paper develops a deep learning method to automate measurement of glomerular basement membrane and podocyte foot process widths in TEM images of podocytopathy mouse models, showing comparable accuracy to manual methods.
Biology Methods and Protocols · Jan 1, 2025Peer-reviewedPathology