Author

D. A. Orens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

a. Sali· 1 shared B. T. Chait· 1 shared J. B. Bonanno· 1 shared M. Brilliantes· 1 shared M. K. Thompson· 1 shared M. P. Rout· 1 shared N. E. Ketaren· 1 shared P. C. Fridy· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

a. Sali

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1 paper

Recent·Most cited

Unique Binding and Stabilization Mechanisms Employed By and Engineered Into Nanobodies.

N. E. Ketaren, P. C. Fridy, V. Malashkevich, T. Sanyal, M. Brilliantes, M. K. Thompson, D. A. Orens, J. B. Bonanno, a. Sali, S. C. Almo, B. T. Chait, M. P. Rout

This study identifies mechanisms enabling nanobodies to bind antigens with high affinity and stability, revealing a conserved region critical for their function and suggesting strategies for their optimization.

bioRxiv · Oct 22, 2023 · PreprintBiochemistry