Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38
O. S. Shin, S. R. Monticelli, C. K. Hjorth, V. Hornet, M. Doyle, D. Abelson, A. I. Kuehne, A. Wang, R. R. Bakken, A. K. Mishra, M. Middlecamp, E. Champney, L. Stuart, D. P. Maurer, J. Li, , J. S. McLellan
The paper identifies non-neutralizing antibodies from CCHFV survivors that target multiple regions on GP38, showing protective efficacy in rodent models.
bioRxiv · Mar 2, 2024Immunology