Simulating clinical trials for model-informed precision dosing: Using warfarin treatment as a use case
D. Augustin, B. Lambert, M. Robinson, K. Wang, D. Gavaghan
This paper develops a framework to simulate clinical trials for model-informed precision dosing, using warfarin treatment to compare three methods: neural network regression, deep reinforcement learning, and PKPD modelling.
bioRxiv · Jul 31, 2023Pharmacology & Toxicology