Author

D. B. Bitoque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. Rosa da Costa· 2 shared S. M. Calado· 2 shared A. V. Oliveira· 1 shared G. A. Silva· 1 shared G. Silva· 1 shared J. Morais· 1 shared R. L. Sequeira· 1 shared S. Simao· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

A. M. Rosa da Costa

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2 papers

Recent·Most cited

Nonviral PDMAEMA Vectors Efficiently Express PDE6beta in a Mouse Model of Retinitis Pigmentosa

D. B. Bitoque, S. M. Calado, A. M. Rosa da Costa, G. Silva

This study demonstrates that PDMAEMA polyplexes efficiently deliver and express the PDE6beta gene in a mouse model of Retinitis Pigmentosa.

bioRxiv · May 4, 2023 · PreprintBioengineering

Human-derived NLS enhance the gene transfer efficiency of chitosan

D. B. Bitoque, J. Morais, A. V. Oliveira, R. L. Sequeira, S. M. Calado, T. M. Fortunato, S. Simao, A. M. Rosa da Costa, G. A. Silva

This study tests human-derived NLS peptides to enhance chitosan-based non-viral gene delivery efficiency, finding a 2-fold increase with co-complexation and covalent ligation.

bioRxiv · Mar 13, 2020Bioengineering