Author

G. Silva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. C. G. Salina· 1 shared A. Fabro· 1 shared A. Garner· 1 shared A. M. Rosa da Costa· 1 shared A. Quadros· 1 shared A. Schneider· 1 shared B. Dixon· 1 shared B. M. Silva· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperImmunology

A. C. G. Salina

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nonviral PDMAEMA Vectors Efficiently Express PDE6beta in a Mouse Model of Retinitis Pigmentosa

D. B. Bitoque, S. M. Calado, A. M. Rosa da Costa, G. Silva

This study demonstrates that PDMAEMA polyplexes efficiently deliver and express the PDE6beta gene in a mouse model of Retinitis Pigmentosa.

bioRxiv · May 4, 2023 · PreprintBioengineering

Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

B. M. Silva, F. P. Veras, G. Gomes, S. Cambier, G. Silva, A. Quadros, D. Caetite, D. Nascimento, C. Silva, J. Silva, S. Damasceno, A. Schneider, F. Beretta, S. Batah, I. Castro, , T. M. Cunha

This study shows that inhibiting C5aR1 signaling reduces neutrophil extracellular traps and improves lung pathology in COVID-19.

bioRxiv · Jul 3, 2022Immunology

Evaluation of PRKACA as a Therapeutic Target for Fibrolamellar Carcinoma

S. S. Schalm, E. O'Hearn, K. Wilson, T. P. LaBranch, G. Silva, Z. Zhang, L. DiPietro, N. Bifulco, R. Woessner, N. Stransky, D. Sappal, R. Campbell, R. Lobbardi, M. Palmer, J. Kim, , K. P. Hoeflich

This study evaluates PRKACA as a therapeutic target for fibrolamellar carcinoma using PDX models and shows that its knockdown or inhibition reduces tumor growth.

bioRxiv · Jan 31, 2022 · PreprintCancer Biology

Commercial vaccines do not confer protection against two genetic strains of Piscirickettsia salmonis, LF-89-like and EM-90-like, in Atlantic salmon.

C. Figueroa, D. Torrealba, B. Morales-Lange, L. Mercado, B. Dixon, P. Conejeros, G. Silva, C. Soto, J. A. Gallardo

This study evaluates the efficacy of a commercial vaccine against two Piscirickettsia salmonis strains in Atlantic salmon, finding no significant survival differences between vaccinated and unvaccinated fish.

bioRxiv · Jan 7, 2021 · PreprintImmunology