D. Beaudet

Huntingtin polyglutamine expansions misdirect axonal transport by perturbing motor and adaptor recruitment

This study shows that HTT polyQ expansions disrupt motor and adaptor recruitment to vesicles, causing transport defects and altered responses to neuroinflammatory stress.

The sets of kinesins and dynein transporting endocytic cargoes determine the effect of tau on their motility

The paper investigates how different motor protein sets on endocytic cargoes influence their motility and response to tau, finding that tau inhibits retrograde transport of early phagosomes more than late phagosomes.

Intramolecular regulation of anillin during cytokinesis

The paper shows that active RhoA relieves autoinhibition of anillin's C2 domain, enabling its recruitment to the equatorial cortex via importin-binding.