Development and Characterization of Patient-Derived Xenografts from Non-Small Cell Lung Cancer Brain Metastases
A. M. Baschnagel, S. Kaushik, A. Durmaz, S. Goldstein, I. M. Ong, L. Abel, P. A. Clark, T. Leal, D. Buehler, G. Iyer, J. G. Scott, R. J. Kimple
This study establishes and characterizes patient-derived xenografts of NSCLC brain metastases, showing strong phenotypic and molecular correlation with original tumors and therapeutic response to targeted treatments.
bioRxiv · Jun 2, 2020Cancer Biology