Author

D. Bustos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Flores-Aldama· 2 shared D. Cabezas-Bratesco· 1 shared G. Robertson· 1 shared J. Li· 1 shared L. Delemotte· 1 shared S. E. Brauchi· 1 shared W. A. Stevens-Sostre· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

L. Flores-Aldama

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2 papers

Recent·Most cited

An intracellular hydrophobic nexus is critical for slow deactivation in hERG channels

W. A. Stevens-Sostre, L. Flores-Aldama, D. Bustos, J. Li, L. Delemotte, G. Robertson

This study identifies a hydrophobic nexus in hERG channels critical for slow deactivation, showing that altering hydrophobicity at this interface accelerates deactivation and links to long QT syndrome mutations.

bioRxiv · Mar 4, 2023 · PreprintBiophysics

Intracellular helix-loop-helix domain modulates inactivation kinetics of mammalian TRPV5 and TRPV6 channels.

L. Flores-Aldama, D. Bustos, D. Cabezas-Bratesco, S. E. Brauchi

The paper identifies amino acids and interactions that determine inactivation kinetics of TRPV5 and TRPV6 channels, proposing the HLH-TDh domain association drives faster inactivation in TRPV6.

bioRxiv · Oct 4, 2022Biophysics