Author

D. C. Viola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:rat· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

N. O. Chahine· 2 shared A. C. Abraham· 1 shared D. N. Kiridly· 1 shared H. E. Jacobsen· 1 shared H. M. Kenawy· 1 shared K. G. Burt· 1 shared L. E. Lisiewski· 1 shared M. K. M. Kim· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

N. O. Chahine

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Nuclear Factor Kappa B Over-Activation in the Intervertebral Disc Leads to Macrophage Recruitment and Severe Disc Degeneration

K. G. Burt, M. K. M. Kim, D. C. Viola, A. C. Abraham, N. O. Chahine

This study shows that prolonged NF-κB activation in intervertebral discs causes severe degeneration by increasing inflammation, catabolic enzymes, and macrophage recruitment, with some mitigation by inflammatory-resolving macrophages.

bioRxiv · Aug 7, 2023 · PreprintBioengineering

Intradiscal Inflammatory Stimulation Induces Spinal Pain Behavior and Intervertebral Disc Degeneration In Vivo

L. E. Lisiewski, H. E. Jacobsen, D. C. Viola, H. M. Kenawy, D. N. Kiridly, N. O. Chahine

This study shows that sustained inflammation in rat intervertebral discs leads to pain behavior and degeneration without structural damage.

bioRxiv · Apr 11, 2022 · PreprintBioengineering