NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response
M. T. Borrello, M. Emma, A. Listi, M. Rubis, S. Coslet, G. Augello, A. Cusimano, D. Cabibi, R. Porcasi, L. Giannitrapani, M. Soresi, G. Pantuso, K. Blyth, G. Montalto, C. L. Pin, , J. L. Iovanna
This study shows NUPR1 protects the liver from lipotoxic injury by enhancing the endoplasmic reticulum stress response and regulating lipid homeostasis through PPAR- signaling.
bioRxiv · Oct 23, 2020Cell Biology