Colicin E1 opens its hinge to plug TolC
S. J. Budiardjo, J. J. Stevens, A. L. Calkins, A. P. Ikujuni, V. K. Wimalasena, E. Firlar, D. Case, J. S. Biteen, J. Kaelber, J. S. G. Slusky
This paper reports the first structure of colicin E1 bound to TolC, showing how it opens its hinge to plug the channel and inhibit antibiotic efflux.
bioRxiv · Aug 24, 2021Biophysics