The structure of monkeypox virus 2'-O-ribose methyltransferase VP39 in complex with sinefungin provides the foundation for inhibitor design
J. Silhan, M. Klima, D. Chalupska, J. Kozic, E. Boura
The paper determines the crystal structure of MPXV VP39 in complex with sinefungin, revealing conserved inhibitor binding that suggests broad antiviral potential.
bioRxiv · Sep 27, 2022 · PreprintMicrobiology