A 3D cell-free bone model shows collagen mineralization is driven and controlled by the matrix
R. H. M. Van der Meijden, D. Daviran, L. Rutten, F. Walboomers, E. Macias-Sanchez, N. Sommerdijk, A. Akiva
This study demonstrates that collagen mineralization in bone is driven by the extracellular matrix, not cellular activity, using a 3D cell-free bone model.
bioRxiv · Oct 24, 2022Biochemistry