Effect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages
J. K. Wychowaniec, E. I. Bektas, A. J. Vernengo, M. Mürner, M. Airoldi, P. S. Tipay, J. Sapudom, J. Teo, D. Eglin, M. D'Este
This paper evaluates how different molecular weights of tyramine-modified hyaluronan affect the polarization of THP-1 and PBMCs-derived macrophages, showing LMW THA drives M1-like polarization while HMW THA induces a mixed profile.
bioRxiv · Jan 11, 2024Bioengineering