Author

J. Sapudom

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Teo· 3 shared A. Alatoom· 2 shared A. J. Vernengo· 1 shared B. C. Quartey· 1 shared D. Eglin· 1 shared E. I. Bektas· 1 shared J. K. Wychowaniec· 1 shared M. Airoldi· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBioengineering

J. Teo

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Author profile →

3 papers

Recent·Most cited

Matrix fibril alignment and density modulate YAP-mediated T-cell immune suppression

J. Sapudom, A. Alatoom, P. Tipay, J. Teo

This study shows that dense and aligned collagen matrices suppress T-cell activation via YAP signaling, suggesting ways to improve immunotherapy by modulating T-cell responses in such environments.

bioRxiv · Mar 19, 2024 · PreprintBioengineering

Effect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages

J. K. Wychowaniec, E. I. Bektas, A. J. Vernengo, M. Mürner, M. Airoldi, P. S. Tipay, J. Sapudom, J. Teo, D. Eglin, M. D'Este

This paper evaluates how different molecular weights of tyramine-modified hyaluronan affect the polarization of THP-1 and PBMCs-derived macrophages, showing LMW THA drives M1-like polarization while HMW THA induces a mixed profile.

bioRxiv · Jan 11, 2024Bioengineering

Tissue-bound hyaluronan molecular weight as a regulator of dendritic cell immune potency

B. C. Quartey, J. Sapudom, M. ElGindi, A. Alatoom, J. Teo

This study investigates how different molecular weights of tissue-bound hyaluronan affect dendritic cell functions, finding that low MW HA enhances immature DC differentiation and antigen uptake, while medium and high MW HA increase cytokine secretion in matured DCs.

bioRxiv · Jun 6, 2023Bioengineering