Recurrent phases of strict protein limitation inhibit tumor growth and restore lifespan in a Drosophila intestinal cancer model
R. M. Pfefferkorn, B. M. Mortzfeld, C. Fink, J. von Frieling, J. Bossen, D. Esser, C. M. Kaleta, P. Rosenstiel, H. Heine, T. Roeder
The paper shows that cyclic severe protein restriction in Drosophila reduces tumor growth, restores gut function, and extends lifespan without the harmful effects of continuous restriction.
bioRxiv · Jan 18, 2023 · PreprintCancer Biology