STAT3 Serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression
J. Balic, H. Albargy, K. Luu, F. Kirby, W. Jayasekara, F. Mansell, D. Garama, N. Baschuk, D. De Nardo, C. Louis, F. Humphries, K. A. Fitzgerald, E. Latz, D. Gough, A. Mansell
This study shows that STAT3 Ser727 phosphorylation is essential for TLR4-induced metabolic reprogramming and IL-1β production in inflammation.
Nature Communications · Jul 30, 2020Peer-reviewedImmunology