Author

D. Garcia-Moreno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:zebrafish· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:imaging· 2 Assay:proteomics· 2

Frequent Co-Authors

V. Mulero· 6 shared M. L. Cayuela· 4 shared A. B. Arroyo· 2 shared F. J. Martinez-Morcillo· 2 shared J. Canton-Sandoval· 2 shared S. D. Tyrkalska· 2 shared A. B. Perez-Oliva· 1 shared A. Garcia-Ayala· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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6 shared papersImmunology

V. Mulero

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Peds1 deficiency in zebrafish results in myeloid cell apoptosis and exacerbated inflammation

A. B. Arroyo, S. D. Tyrkalska, E. Bastida-Martinez, A. J. Monera-Girona, J. Canton-Sandoval, M. Bernal-Carrion, D. Garcia-Moreno, M. Elias-Arnanz, V. Mulero

This study shows that Peds1 deficiency in zebrafish causes myeloid cell apoptosis and worsened inflammation, with plasmalogen supplementation improving outcomes.

bioRxiv · Sep 26, 2023Immunology

A zebrafish model of COVID-19-associated cytokine storm syndrome reveals differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.

S. D. Tyrkalska, A. Martinez-Lopez, A. B. Arroyo, F. J. Martinez-Morcillo, S. Candel, P. Mesa-del-Castillo, D. Garcia-Moreno, M. L. Cayuela, V. Mulero

This paper uses a zebrafish model to study the proinflammatory effects of SARS-CoV-2 Spike proteins from different variants, finding differential inflammatory responses and potential therapeutic targets.

bioRxiv · Dec 5, 2021 · PreprintImmunology

NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos

F. J. Martinez-Morcillo, J. Canton-Sandoval, F. J. Martinez-Navarro, I. cabas, I. Martinez-Vicente, J. Armistead, J. Hatzold, A. Lopez-Munoz, T. Martinez-Menchon, R. Corbalan-Velez, J. Lacal, M. Hammerschmidt, J. C. Garcia-Borron, A. Garcia-Ayala, M. L. Cayuela, , V. Mulero

This study shows that NAMPT-derived NAD+ fuels PARP1 to drive skin inflammation via parthanatos in psoriasis models.

bioRxiv · Feb 19, 2021Immunology

TERT-mediated induction of MIR500A contributes to tumor invasiveness by targeting Hedgehog pathway

M. Bernabe-Garcia, E. Martinez-Balsalobre, D. Garcia-Moreno, J. Garcia-Castillo, B. Revilla-Nuin, E. Blanco-Alcaina, V. Mulero, F. Alcaraz-Perez, M. L. Cayuela

The paper shows TERT promotes cancer invasiveness by inducing MIR500A, which suppresses Hedgehog pathway genes.

bioRxiv · Feb 18, 2020 · PreprintCancer Biology

SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment

E. Gomez-Abenza, S. Ibanez-Molero, D. Garcia-Moreno, I. Fuentes-Martinez, L. Zon, M. C. Mione, M. L. Cayuela, C. Gabellini, V. Mulero

The paper shows Spint1a deficiency in zebrafish promotes SKCM aggressiveness by enhancing oncogenic transformation, regulating tumor-immune crosstalk, and accelerating metastasis.

bioRxiv · Apr 16, 2019Cancer Biology

Olfactory sensory neurons mediate ultra-rapid antiviral immune responses in teleosts in a TrkA-dependent manner

A. Sepahi, A. Kraus, C. A. Johnston, J. Galindo-Villegas, C. Kelly, D. Garcia-Moreno, P. Munoz, V. Mulero, M. Huertas, I. Salinas

This study shows that olfactory sensory neurons in teleosts detect viruses via TrkA receptor interaction, triggering local immune responses and reducing systemic inflammation.

bioRxiv · Nov 6, 2018Immunology