Author

D. Gotthardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. Bykov· 1 shared A. Dupanovic· 1 shared A. Hiesinger· 1 shared A. R. Poetsch· 1 shared A. Witalisz-Siepracka· 1 shared B. Kovacic· 1 shared B. Maurer· 1 shared D. Emminger· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Bykov

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2 papers

Recent·Most cited

A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia

K. Klein, S. Kollmann, J. List, A. Hiesinger, J. Kender, M. Rhandawa, J. Trifinopoulos, B. Maurer, R. Grausenburger, R. Moriggl, T. Ruelicke, A. Witalisz-Siepracka, W. Walter, G. Hoermann, V. Sexl, D. Gotthardt

This paper creates a mouse model with a STAT5BN642H mutation to study NK-cell leukemia and finds it leads to both indolent and aggressive forms of the disease.

Blood · Jun 13, 2024Peer-reviewedCancer Biology

Natural killer cell cytotoxicity shapes the clonal evolution of B cell leukaemia

M. C. Buri, M. R. Shoeb, A. Bykov, P. Repiscak, H. Baik, A. Dupanovic, F. O. David, B. Kovacic, F. Hall-Glenn, S. Dopa, J. Urbanus, L. Sippl, S. Stofner, D. Emminger, J. Cosgrove, , E. M. Putz

This study shows NK cells influence all phases of cancer immunoediting in B-ALL, promoting resistant clones through selective pressure and identifying LY6E as a marker of poor prognosis.

bioRxiv · Nov 16, 2023Cancer Biology