Cooperativity of c-MYC with Krüppel-Like Factor 6 Splice Variant 1 induces phenotypic plasticity and promotes prostate cancer progression and metastasis
S. Izadmehr, H. Fernandez-Hernandez, D. Wiredja, A. Kirschenbaum, C. Lee-Poturalski, P. Tavassoli, S. Yao, D. Schlatzer, D. Hoon, A. DiFeo, A. C. Levine, J.-M. Mosquera, M. D. Galsky, C. Cordon-Cardo, G. Narla
This study identifies the cooperative role of c-MYC and KLF6-SV1 in promoting prostate cancer progression and metastasis through proteomic and genetic analyses in mouse models.
bioRxiv · Jan 30, 2024 · PreprintCancer Biology