Genome-wide effects of the antimicrobial peptide apidaecin on translation termination
K. Mangano, T. FLorin, X. Shao, D. Klepacki, I. Chelysheva, Z. Ignatova, Y. Gao, A. Mankin, N. Vazquez-Laslop
This study shows that the antimicrobial peptide apidaecin inhibits translation by arresting ribosomes at stop codons and causing stop codon bypass, leading to C-terminal extensions on proteins.
bioRxiv · May 17, 2020Biochemistry