Author

K. Mangano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

A. M. Stringer· 1 shared A. Mankin· 1 shared C. Smith· 1 shared D. Klepacki· 1 shared I. Chelysheva· 1 shared J. T. Wade· 1 shared N. Vazquez-Laslop· 1 shared T. FLorin· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. M. Stringer

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2 papers

Recent·Most cited

Identification of novel translated small ORFs in Escherichia coli using complementary ribosome profiling approaches

A. M. Stringer, C. Smith, K. Mangano, J. T. Wade

The paper identifies 365 novel small ORFs in E. coli using ribosome profiling with antibiotics to stall ribosomes at start and stop codons, showing many encode unstable proteins not under purifying selection.

bioRxiv · Jul 2, 2021Microbiology

Genome-wide effects of the antimicrobial peptide apidaecin on translation termination

K. Mangano, T. FLorin, X. Shao, D. Klepacki, I. Chelysheva, Z. Ignatova, Y. Gao, A. Mankin, N. Vazquez-Laslop

This study shows that the antimicrobial peptide apidaecin inhibits translation by arresting ribosomes at stop codons and causing stop codon bypass, leading to C-terminal extensions on proteins.

bioRxiv · May 17, 2020Biochemistry