Author

D. L. Ivanova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:flow cytometry· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

J. Gigley· 2 shared S. L. Denton· 2 shared D. Rach· 1 shared G. M. Saltz· 1 shared I. R. Dunay· 1 shared J. Materi· 1 shared J. P. Gigley· 1 shared K. D. Fettel· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

J. Gigley

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NK cells negatively regulate CD8 T cells to promote immune exhaustion and chronic Toxoplasma gondii infection

J. P. Gigley, D. L. Ivanova, R. Krempels, S. L. Denton, K. D. Fettel, G. M. Saltz, D. Rach, R. Fatima, T. Mundhenke, J. Materi, I. R. Dunay

This study shows that NK cells in chronic Toxoplasma gondii infection promote CD8+ T cell exhaustion and parasite persistence by developing a modified NK cell population that suppresses CD8+ T cell function.

bioRxiv · Dec 5, 2019Immunology

Anti-Asialo GM1 treatment during secondary Toxoplasma gondii infection is lethal and depletes T cells

D. L. Ivanova, S. L. Denton, J. Gigley

This study shows that anti-ASGM1 treatment during secondary Toxoplasma gondii infection causes 100% mortality and depletes T cells, particularly CD8+ effector T cells, highlighting ASGM1 as a marker of activated T cells.

bioRxiv · Feb 18, 2019 · PreprintImmunology

The IL-12 and IL-23-Dependent NK Cell Response is Essential For Protective Immunity Against Secondary Toxoplasma gondii Infection.

D. L. Ivanova, T. M. Mundhenke, J. Gigley

This study shows NK cells are essential for protective immunity against secondary Toxoplasma gondii infection, with their response dependent on IL-12 and IL-23.

bioRxiv · Feb 12, 2019Immunology