Loss of macp{Psi} ribosomal RNA modification is a major feature of cancer
A. Babaian, K. Rothe, D. Girodat, I. Minia, S. Djondovic, M. Milek, S. E. Spencer Miko, H.-J. Wieden, M. Landthaler, G. B. Morin, D. L. Mager
The paper identifies a cancer-specific rRNA modification loss in multiple cancers, linking it to oncogenic translational signatures and potential therapeutic targets.
bioRxiv · Feb 6, 2020Cancer Biology