Author

M. Milek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

D. Beule· 2 shared A. Babaian· 1 shared A. Diefenbach· 1 shared A. Fagundes· 1 shared A. Rabes· 1 shared A. Trinks· 1 shared B. Opitz· 1 shared C. S. N. Klose· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

D. Beule

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota

I. Roewekamp, L. Maschirow, A. Rabes, F. Fiocca Vernengo, G. A. Heinz, M.-F. Mashreghi, S. Caesar, M. Milek, A. Fagundes, S.-M. Wienhold, G. Nouailles, L. Yao, D. Bruder, J. Boehme, M. Puzianowska-Kuznicka, , B. Opitz

This study shows IL-33 reduces IL-22 production in innate lymphoid cells, increasing resistance to Streptococcus pneumoniae infection, and links genetic variation in IL-33 signaling to human pneumonia.

bioRxiv · Jul 19, 2023Immunology

Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and formalin-fixed paraffin-embedded (FFPE) lung cancer tissue

A. Trinks, M. Milek, D. Beule, J. Kluge, S. Florian, C. Sers, D. Horst, M. Morkel, P. Bischoff

The paper compares single-cell RNA sequencing from fresh, cryopreserved, and FFPE lung cancer tissues, finding FFPE tissues can reliably detect clinically relevant features.

bioRxiv · Apr 25, 2023Pathology

Loss of macp{Psi} ribosomal RNA modification is a major feature of cancer

A. Babaian, K. Rothe, D. Girodat, I. Minia, S. Djondovic, M. Milek, S. E. Spencer Miko, H.-J. Wieden, M. Landthaler, G. B. Morin, D. L. Mager

The paper identifies a cancer-specific rRNA modification loss in multiple cancers, linking it to oncogenic translational signatures and potential therapeutic targets.

bioRxiv · Feb 6, 2020Cancer Biology