Selectivity among anti-σ factors by Mycobacterium tuberculosis ClpX influences intracellular levels of Extracytoplasmic Function σ factors
A. C. Joshi, P. Kaur, R. Nair, D. Lele, V. K. Nandicoori, B. Gopal
This study shows that mutations in the degron of anti-σ factors in M. tuberculosis affect ClpX-mediated proteolysis, thereby regulating the release of ECF σ factors and gene expression.
bioRxiv · Dec 10, 2018Biochemistry