Multiplex secretome engineering enhances recombinant protein production and purity
S. Kol, D. Ley, T. Wulff, M. Decker, J. Arnsdorf, J. M. Gutierrez, A. W. Chiang, L. E. Pedersen, H. F. Kildegaard, G. M. Lee, N. Lewis
This study shows that deleting multiple host cell proteins in CHO cells improves recombinant protein production and purity through enhanced purification efficiency.
bioRxiv · May 24, 2019Bioengineering