A Tethered Ligand Assay to Probe SARS-CoV-2:ACE2 Interactions
M. S. Bauer, S. Gruber, A. Hausch, L. F. Milles, T. Nicolaus, L. C. Schendel, P. Lopez Navajas, E. Procko, D. Lietha, R. C. Bernardi, H. E. Gaub, J. Lipfert
This paper introduces a tethered ligand assay to study SARS-CoV-2:ACE2 interactions under mechanical force, showing higher stability and lower dissociation rates compared to SARS-CoV-1.
bioRxiv · Aug 8, 2021 · PreprintBiophysics