Author

A. Hausch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

J. Lipfert· 3 shared S. Gruber· 3 shared H. E. Gaub· 2 shared L. F. Milles· 2 shared M. S. Bauer· 2 shared R. C. Bernardi· 2 shared T. Nicolaus· 2 shared A. Loef· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBiophysics

J. Lipfert

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Author profile →

3 papers

Recent·Most cited

Effects of Variants of Concern Mutations on the Force-Stability of the SARS-CoV-2:ACE2 Interface and Virus Transmissibility

M. S. Bauer, S. Gruber, A. Hausch, M. C. R. Melo, P. S. F. C. Gomes, T. Nicolaus, L. F. Milles, R. C. Bernardi, H. E. Gaub, J. Lipfert

This study examines how mutations in SARS-CoV-2 variants affect the force-stability of the SARS-CoV-2:ACE2 interface and virus transmissibility.

bioRxiv · Jan 6, 2023 · PreprintBiophysics

A Conformational Transition of Von Willebrand Factor's D'D3 Domain Primes It For Multimerization

S. Gruber, A. Loef, A. Hausch, R. Joehr, T. Obser, G. Koenig, R. Schneppenheim, M. A. Brehm, M. Benoit, J. Lipfert

This study uses single-molecule force spectroscopy to show that a conformational change in VWF's DD3 domain, triggered by pH changes and stabilized by FVIII, primes it for multimerization.

bioRxiv · Nov 29, 2021 · PreprintBiophysics

A Tethered Ligand Assay to Probe SARS-CoV-2:ACE2 Interactions

M. S. Bauer, S. Gruber, A. Hausch, L. F. Milles, T. Nicolaus, L. C. Schendel, P. Lopez Navajas, E. Procko, D. Lietha, R. C. Bernardi, H. E. Gaub, J. Lipfert

This paper introduces a tethered ligand assay to study SARS-CoV-2:ACE2 interactions under mechanical force, showing higher stability and lower dissociation rates compared to SARS-CoV-1.

bioRxiv · Aug 8, 2021 · PreprintBiophysics