Simulation-based Reconstructed Diffusion unveils the effect of aging on protein diffusion in Escherichia coli
L. Mantovanelli, D. Linnik, M. Punter, H. Kojakhmetov, W. Smigiel, B. Poolman
The paper develops SbRD to correct diffusion coefficients in E. coli and finds slower diffusion at cell poles compared to the nucleoid, independent of polysomes, with asymmetry due to aging.
bioRxiv · Apr 10, 2023 · PreprintBiophysics