Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics
B. Furtwängler, N. Üresin, K. Motamedchaboki, R. Huguet, D. Lopez-Ferrer, V. Zabrouskov, B. T. Porse, E. M. Schoof
The paper introduces RETICLE, a new acquisition strategy for multiplexed single-cell proteomics that improves proteome coverage and quantitative accuracy using real-time search and SPS-MS3 on a Tribrid mass spectrometer.
bioRxiv · Aug 16, 2021Biochemistry