Author

V. Zabrouskov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:protein folding & dynamics· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. Makarov· 2 shared A. Pashkova· 2 shared A. Peterson· 2 shared C. Hock· 2 shared D. Hermanson· 2 shared E. Denisov· 2 shared H. Stewart· 2 shared J. Petzoldt· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. Makarov

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evaluating the performance of the Astral mass analyzer for quantitative proteomics using data independent acquisition

L. R. Heil, N. E. Damoc, T. N. Arrey, A. Pashkova, E. Denisov, J. Petzoldt, A. Peterson, C. Hsu, B. C. Searle, N. Shulman, M. Riffle, B. Connolly, B. X. MacLean, P. M. Remes, M. Senko, , M. J. MacCoss

The paper evaluates the Astral mass analyzer's performance in quantitative proteomics, showing it quantifies 5 times more peptides per unit time than existing Orbitrap mass spectrometers and detects over 5,000 plasma proteins.

bioRxiv · Jun 3, 2023 · PreprintBiochemistry

Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

H. Stewart, D. Grinfeld, A. Giannakopulos, J. Petzoldt, T. Shanley, M. Garland, E. Denisov, A. Peterson, E. Damoc, M. Zeller, T. Arrey, A. Pashkova, S. Renuse, A. Hakimi, A. Kuehn, , C. Hock

The paper introduces a new hybrid mass spectrometer combining Orbitrap and Astral analyzers to enable faster and more sensitive high-resolution accurate mass MS/MS spectra acquisition for proteomics.

bioRxiv · Jun 2, 2023Cell Biology

Novel Real-Time Library Search driven data acquisition strategy for identification and characterization of metabolites.

B. Bills, W. D. Barshop, S. Sharma, J. Canterbury, A. M. Robitaille, M. W. Senko, V. Zabrouskov

The paper introduces a real-time data acquisition strategy, Met-IQ, that improves metabolite identification by selectively triggering MS3 scans based on spectral similarity, resulting in 55% more unique metabolite identifications.

bioRxiv · Oct 7, 2021Pharmacology & Toxicology

Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

B. Furtwängler, N. Üresin, K. Motamedchaboki, R. Huguet, D. Lopez-Ferrer, V. Zabrouskov, B. T. Porse, E. M. Schoof

The paper introduces RETICLE, a new acquisition strategy for multiplexed single-cell proteomics that improves proteome coverage and quantitative accuracy using real-time search and SPS-MS3 on a Tribrid mass spectrometer.

bioRxiv · Aug 16, 2021Biochemistry

Multiplexed Single Ion Mass Spectrometry Improves Measurement of Proteoforms and Their Complexes

J. O. Kafader, R. D. Melani, K. R. Durbin, B. Ikwuagwu, B. P. Early, R. T. Fellers, S. C. Beu, V. Zabrouskov, A. A. Makarov, J. T. Maze, D. L. Shinholt, P. F. Yip, D. Tullman-Ereck, M. W. Senko, P. D. Compton, N. L. Kelleher

This paper introduces a new Orbitrap-based single ion analysis method that improves the measurement of proteoforms and their complexes by directly determining ion charge.

bioRxiv · Jul 26, 2019 · PreprintBiochemistry