Author

D. Lousa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1

Frequent Co-Authors

C. M. Soares· 2 shared C. Barria· 1 shared C. M. Arraiano· 1 shared C. Penha-Goncalves· 1 shared C. S. Souza· 1 shared C. Soares· 1 shared F. Ferreira· 1 shared H. Soares· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

C. M. Soares

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility

M. F. Valerio, L. Borges-Araujo, M. N. Melo, D. Lousa, C. M. Soares

This study investigates how SARS-CoV-2 variants affect RBD conformational dynamics and ACE2 accessibility using molecular dynamics simulations.

bioRxiv · Nov 30, 2021 · PreprintBiophysics

Amino acids 484 and 494 of SARS-CoV-2 spike are hotspots of immune evasion affecting antibody but not ACE2 binding

M. Alenquer, F. Ferreira, D. Lousa, M. Valerio, M. Medina-Lopes, M.-L. Bergman, J. Goncalves, J. Demengeot, R. B. Leite, J. Lilue, Z. Ning, C. Penha-Goncalves, H. Soares, C. Soares, M. J. Amorim

bioRxiv · Apr 22, 2021 · PreprintImmunology

New targets for drug design: Importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2

M. Saramago, C. Barria, V. Costa, C. S. Souza, S. C. Viegas, S. Domingues, D. Lousa, C. M. Soares, C. M. Arraiano, R. G. Matos

This study characterizes the nsp14-nsp10 complex in SARS-CoV-2, showing its role in ExoN activity and identifying potential drug targets.

bioRxiv · Jan 7, 2021Microbiology