MicrobiologybioRxivPreprint
Influenza A virus activates the unfolded protein response and induces the accumulation of insoluble protein aggregates that are essential for efficient viral propagation
DOI 10.1101/2023.09.11.557148
Author
M. J. Amorim
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2018-2023 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship7 papers
Recent·Most cited
- Cell BiologyeLifePeer-reviewed
Rules for hardening influenza A virus liquid condensates
T. A. Etibor, S. Vale-Costa, S. Sridharan…·M. J. Amorim
This study demonstrates that modulating transient interactions in influenza A virus condensates is more effective for hardening than temperature or concentration changes, offering a strategy for antiviral drug design.
DOI 10.7554/elife.85182 - Cell BiologybioRxivPreprint
ATG9A regulates dissociation of recycling endosomes from microtubules leading to formation of influenza A virus liquid condensates
S. Vale-Costa, T. A. Etibor, D. Bras…·M. J. Amorim
This study shows ATG9A facilitates the formation of influenza A virus liquid condensates by removing Rab11a-recycling endosomes from microtubules, enabling their condensation near the ER.
DOI 10.1101/2022.12.21.521536 - Cell BiologybioRxiv
PI4P and BLOC-1 remodel endosomal membranes into tubules
R. A. Jani, A. Di Cicco, T. Keren-Kaplan…·C. Delevoye
This study shows how PI4P and BLOC-1 coordinate to form and stabilize endosomal tubules, essential for membrane remodeling and pathogen trafficking.
DOI 10.1083/jcb.202110132 - ImmunologybioRxivPreprint
Amino acids 484 and 494 of SARS-CoV-2 spike are hotspots of immune evasion affecting antibody but not ACE2 binding
DOI 10.1101/2021.04.22.441007 - MicrobiologybioRxiv
Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology
N. B. Santos, Z. E. Vaz da Silva, C. Gomes…·M. J. Amorim
This study shows that complement decay-accelerating factor (DAF) modulates influenza A virus (IAV) lung immunopathology by enhancing complement activation through interactions with viral proteins HA and NA, without affecting viral loads.
DOI 10.1371/journal.ppat.1009381 - MicrobiologybioRxiv
Pleotropic effects of mutations in the effector domain of influenza A virus NS1 protein
C. F. Pereira, H. M. Wise, D. Kurian…·P. Digard
The paper investigates how mutations in the NS1 protein of influenza A virus affect its ability to promote viral mRNA nuclear export and interacts with cellular factors.
DOI 10.1186/s13104-018-3779-6